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Search Results for " rna polymerase ii-in-2 "

4

Compounds

Cat No. Product Name Synonyms Targets
T74631 RNA polymerase II-IN-2
RNA polymerase II-IN-2 (compound 20iii), a potent inhibitor of RNA polymerase II (Pol II) with a K i value of 9.5 nM, demonstrates cytotoxicity against cancer cells, exhibiting toxicity levels 2 and 5 times higher than α...
T63368 CDK7-IN-2
CDK7-IN-2 is a potent inhibitor of CDK7. CDK7 is involved in transcription initiation using phosphorylation of the Rbpl subunit of RNA polymerase II (RNAPII), which is associated with temporal control of cell cycle and t...
T69931 MFH290
MFH290 is a novel cysteine (Cys)-directed covalent inhibitor of CDK12/13. MFH290 forms a covalent bond with Cys-1039 of CDK12, exhibits excellent kinome selectivity, inhibits the phosphorylation of serine-2 in the C-term...
T36745 CDPCP
cDPCP is a platinum-containing DNA-crosslinking agent.1Unlike cisplatin or oxaliplatin , cDPCP forms monofunctional DNA adducts. It is transported into cells by organic cation transporter 1 (OCT1) and OCT2, inhibiting pr...
TargetMol